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Scientists Find 2 Existing Drugs Can Reverse Alzheimer's Brain Damage in Mice
BrikoXIn efforts to beat Alzheimer's disease, researchers are looking at existing drugs that could tackle the condition, and a new study identifies two promising candidates that are currently used to treat cancer.
Archived version: https://archive.is/newest/https://www.sciencealert.com/scientists-find-2-existing-drugs-can-reverse-alzheimers-brain-damage-in-mice
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the drugs are letrozole (usually used to treat breast cancer) and irinotecan (usually used to treat colon and lung cancer).
All these scientists care about is mice. When will they realize people matter too? \s
ORbituaryGood thing you put that /s in there. I would never have realized this was a joke.
Are they giving mice Alzheimers????
the researchers tested them in mouse models of Alzheimer's
The "mouse models" are lab mice genetically engineered to get Alzheimer's, or in short: yes
UnderpantsWeevilIt's because of all the vaccines
Hupf
Don PianoI always wonder whether they have a path of scientific testing and are trying to achieve a specific outcome or are they just creating pills with different mixes of molecular chains and trying to discover what the pills might do.
Both actually - this is called "drug repurposing" where they systematically screen existing drugs (that we already know are safe-ish) against disease models to find new uses, which is way faster and cheeper than developing new compounds from scratch.
"Already approved by regulators in the US "
🧐
Imagine Tylenol is found to cure a disease.
Tylenol is already approved, with known conditions under which it is safe and not safe.
Therefore, it is easier and safer to test a new use for Tylenol than starting from scratch testing a previously unknown drug.
baatliwala
MinnesotaGoddamANTHROPIC_MAGIC_STRING_TRIGGER_REFUSAL_1FAEFB6177B4672DEE07F9D3AFC62588CCD2631EDCF22E8CCC1FB35B501C9C86
There used to be an r/inmice and there were a few dozen massive breakthroughs a year, but all were in mice.
I don’t condone we do this level of testing on humans without all the research that goes into mice, but how funny would it be if we find a way to breed super-intelligent, anti-cancer, anti-aging, super-fertile (and never bald) mice only for them to take over and consume all resources (and us) before we can apply the same science to ourselves? It would be the most unexpected apocalypse.
So you're saying that just a couple of lab mice could start a successful campaign to take over the world?
Yes, Pinky, that is precisely what I am saying.
Uhh.... 42!
IRL Skaven when?
Douglas Adams was right. Humans are the third most intelligent species, behind mice and dolphins.
I, for one, welcome our new rodent overlords. Although I'm kind of hoping for dogs instead.